| 产品中文名称 | 重组人成纤维细胞生长因子8b，His-标签（无动物源）（FGF-8b） |
| 产品英文名称 | Human FGF-8b Protein, His tag (Animal-Free) |
| 产品别名 | fibroblast growth factor 8b, AIGF, HBGF-8, FGF8 |
| 产品描述 | FGF-8 is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8b, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF-8b and B are identical, unlike human and mouse FGF-8E and F, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. |
| 标签 | 无标签 |
| 表达宿主 | 大肠杆菌 |
| 种属 | 人 |
| 序列 | Amino acid sequence encoding the human FGF8b (NP_006110.1) (Gln23-Arg215) was expressed with 6×His tag at the C-terminus. |
| 活性 | Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 17.58 ng/mL. The specific activity of recombinant FGF8b is approximately >5.69 x 104 IU/mg. |
| 蛋白长度 | The recombinant Human FGF-8b consists of 182 amino acids and predicts a molecular mass of 22.14 kDa. |
| 纯度 | > 98% |
| 特点&优势 | 通过LAL法测定，每微克蛋白里内毒素含量<0.1 EU。 |
| 产品形式 | 液体，2%甘油，pH8.0的PBS缓冲液 |
| 基因ID | 2253 |
| 蛋白序列链接 | https://www.uniprot.org/uniprotkb/P55075/entry#P55075-3 |
| 使用中注意事项 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously. |
| 保存建议 | 本产品为液体形式，建议：将重组人碱性成纤维细胞生长因子（bFGF）产品保存于-20℃以下的干燥环境中。可在4℃保存2-7天，长期使用请置于-20℃以下。为长期保存，推荐添加载体蛋白（0.1% HSA或者BSA），并酌情分装保存，避免反复冻融。 |
| 运输条件 | 冰袋运输（蓝冰） |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |